CHU Sainte-Justine Research Center
Early-stage mother and child clinical research key to therapeutic solutions
The Sainte-Justine University Hospital Center (CHU Sainte-Justine) is a mother and child pediatric hospital known worldwide for medical care, teaching and research into novel therapies for young patients, from conception through gestation to adulthood.
The early-stage clinical research activities at the CHU Sainte-Justine are aimed at better understanding rare and complex diseases and participating in the development of innovative treatments that benefit a patient population that generates 3,500 births, 83,300 emergency visits and 223,000 outpatient visits every year. In collaboration with the Charles Bruneau Foundation, the hospital implemented a phase l pediatric oncology unit, the Unité de recherche clinique précoce en hématologie-oncologie (URCP-HO, clinical research unit in hematology-oncology) and launched the SIGNATURE program in genomics and immunotherapy for pediatric cancers.
Areas of expertise
The CHU Sainte-Justine stands out for the innovative design of its perinatal and rare disease clinical trials. More specifically, the CHU Sainte-Justine’s physician-researchers develop and actively participate in phase I and II studies for pediatric diseases, such as neurodevelopmental (such as epilepsy), gastrointestinal and infectious diseases.
- Research team highly specialized in conducting phase I clinical research: collecting samples for pharmacokinetic assays for pediatric patients, assessment of palatability and acceptability, high-level safety framework, close monitoring of adverse effects, completion of case report forms (CRF) in under 48 hours;
- Centralized expertise to manage large-scale multicentre studies: biostatistics, bioinformatics, medical publishing, data management and electronic data capture system;
- Collaboration with an extensive North American hospital network as part of the KidsCAN initiative (clinical trials for children)/MICYRN (Maternal Infant Child and Youth Research Network) for launching multi-site clinical trials;
- Development of pediatric formulations suitable for children at the CHU Sainte-Justine’s Goodman Pediatric Formulations Centre;
- Clinical genomics analysis at the Quebec Centre for Clinical Genomics.
Investigators specializing in phase I trials
Dr. Yvan Samson – Hematologist-oncologist – solid tumours and brain tumours
Dr. Pierre Teira – Hematologist-oncologist – neuroblastoma: mechanisms, new therapeutic approaches
Coordinator, Early-Stage Clinical Research Program
CHU Sainte-Justine Research Centre
T: 514.345.4931, ext. 6875