The Neuro | Montreal Neurological Institute and Hospital

The Neuro | Montreal Neurological Institute and Hospital

A global leader in research on rare and terminal neurological diseases

Dr. Ziv Gan-Or
Co-Director, Clinical Research Unit
Montreal Neurological Institute and Hospital

Dr. Massimo Pandolfo
Co-Director, Clinical Research Unit
Montreal Neurological Institute and Hospital

A global leader in brain research and advanced patient care, the Montreal Neurological Institute and Hospital (The Neuro) conducts 20% of all phase I clinical trials in Canada and recruits patients in many other countries.

The Neuro’s Clinical Research Unit (CRU) manages more than 110 clinical trials every year (phases 0 to IV), including about a dozen phase I programs for rare and terminal neurological diseases. A model organization focused on performance and patient safety, the CRU boasts some fifty specialized employees. The research team shares the premises of the hospital to facilitate patient recruitment.


Multiple sclerosis, amyotrophic lateral sclerosis, oculopharyngeal muscular dystrophy, facioscapulohumeral muscular dystrophy, Duchenne muscular dystrophy, spinal muscular atrophy, rare forms of migraines, multiple system atrophy, genetic forms of Parkinson’s disease, rare forms of dementia, primary brain tumours, autism, stroke and spinal column disorders.


  • Clinical and preclinical studies sponsored by pharmaceutical companies or funding agencies such as the National Institutes of Health (NIH);
  • Drug discovery platform: preclinical trials (phase 0) for proof-of-concept validation before a first human administration trial;
  • Centralized resources to support investigators: staffing, ethics review, budgets, contracts, etc.;
  • Clinical research mentoring and training program.


  • Unit and team dedicated to phase I trials;
  • Two treatment rooms for visits of less than 24 hours;
  • A clean room dedicated to clinical trials of stem cells and gene therapies.

Investigators specializing in phase I trials

Dr. Simon Ducharme – Neuropsychiatry, frontotemporal dementia, early-onset dementia, neuropsychiatric aspects of epilepsy and non-epileptic psychogenic seizures

Dr. Ronald Postuma – Movement disorders

Dr. Angela Genge – ALS, EMG, neurodegenerative disorders



Mathias Couillard
Manager, Clinical Research Unit – The Neuro, Faculty of Medicine, McGill University
3801 University, Room 207-L, Montreal, Quebec, Canada H3A 2B4
 T: 514 398-5500 |